University of Pennsylvania

Garret FitzGerald, MD, McNeil Professor in Translational Medicine and Therapeutics at the University of Pennsylvania School of Medicine; Chair of the Department of Pharmacology; and Director of the Institute for Translational Medicine and Therapeutics received the J. Allyn Taylo...

Rita Balice-Gordon, PhD, professor of Neuroscience, and Josep Dalmau, MD, PhD, professor of Neurology, both of the University of Pennsylvania School of Medicine, have been awarded the McKnight Neuroscience of Brain Disorders Award for 2010. Balice-Gordon and Dalmau discovered tha...

Chronic wounds, including venous leg ulcers which are caused by poor circulation in the veins of the legs, are difficult and expensive to treat. Researchers at the University of Pennsylvania School of Medicine have developed the first targeted, short-term delivery method using gene t...

During the busy holiday season, four Penn Medicine locations will pause to honor friends, family and loved ones by lighting trees. Penn Wissahickon Hospice, a division of the Penn Home Care & Hospice Service and part of the University of Pennsylvania Health System, holds the Light U...

Scientists at the University of Pennsylvania School of Medicine discovered that a dietary antioxidant found in such vegetables as broccoli and cauliflower protects cells from damage caused by chemicals generated during the body’s inflammatory response to infection and injury. Th...

An international team of scientists, led by researchers at the University of Pennsylvania School of Medicine, is taking the first step in developing a treatment for a rare genetic disorder called fibrodysplasia ossificans progressiva (FOP), in which the body’s skeletal muscles and...

David A. Asch, MD, MBA, the Robert D. Eilers Professor of Medicine and Health Care Management and Economics at the University of Pennsylvania School of Medicine and the Wharton School, was presented with the Alpha Omega Alpha Robert J. Glaser Distinguished Teacher Award by the Associatio...

Among eligible Medicare beneficiaries, increased use of carotid arterial stenting (CAS) procedures to treat carotid stenosis—the narrowing of the carotid artery—is associated with higher rates of mortality and adverse clinical outcomes, including heart attack and stroke, acco...

Arthur H. Rubenstein, MBBCh, Executive Vice President of the University of Pennsylvania for the Health System, and Dean, School of Medicine, will receive the Abraham Flexner Award for Distinguished Service to Medical Education from the Association of American Medical Colleges (AAM...

In addition to building muscle, weightlifting is also a prescription for self-esteem among breast cancer survivors, according to new University of Pennsylvania School of Medicine research. Breast cancer survivors who lift weights regularly feel better about bodies and their appea...

While studying how the heart is formed, scientists at the University of Pennsylvania School of Medicine serendipitously found a novel cellular source of atrial fibrillation (AF), the most common type of abnormal heart beat. Jonathan Epstein, MD, William Wikoff Smith Professor, and C...

Enrolling in a weight loss program with a family member or friend appears to enhance weight loss among African Americans, but only if the involved partner attends sessions frequently or also loses weight, according to a report in the October 26 issue of Archives of Internal Medicine. Obe...

The presence of a gene can predict when a traumatic brain injury (TBI) will lead to early symptoms of Alzheimer’s disease, according to a new study from neuroscientists at the University of Pennsylvania School of Medicine. Amyloid plaque deposits, known primarily for their role in Alzh...

University of Pennsylvania School of Medicine researchers, along with colleagues at the University of Washington and the University of Toronto, have received $8 million for stem-cell research. The Penn group is one of nine research hubs awarded $170 million over the next seven years b...

University of Pennsylvania School of Medicine investigators are among the 42 recipients of a new National Institutes of Health (NIH) award that encourages investigators to challenge the status quo with innovative ideas. NIH expects to make competing awards totaling $30 million to t...

Four professors from the University of Pennsylvania School of Medicine have been elected as members of the Institute of Medicine (IOM), one of the nation's highest honors in biomedicine. The new members bring Penn's total to 72, out of a total active membership of 1,610. Overall, the IOM n...

In a first-of its-kind study, epidemiologists at the University of Pennsylvania School of Medicine found that, on average, guns did not protect those who possessed them from being shot in an assault. The study estimated that people with a gun were 4.5 times more likely to be shot in an assau...

Aromatase inhibitors, the same drugs that have buoyed long-term survival rates among breast cancer patients, also carry side effects including joint pain so severe that many patients discontinue these lifesaving medicines. New University of Pennsylvania School of Medicine resear...

University of Pennsylvania geneticist Sarah A. Tishkoff, PhD is among 18 recipients of the 2009 National Institutes of Health’s Pioneer Award. Tishkoff, the David and Lyn Silfen University Associate Professor and a Penn Integrates Knowledge Professor, is a leading global expert in hu...

While scientists have known for several years that our body’s internal clock helps regulate many biological processes, researchers have found that the reverse is also true: Many common biological processes – including insulin metabolism – regulate the clock, according to a new stud...

Best known as the oxygen-carrying component of hemoglobin, the protein that makes blood red, heme also plays a role in chemical detoxification and energy metabolism within the cell. Heme levels are tightly maintained, and with good reason: Too little heme prevents cell growth and divi...

Shirin Karsan, a recent graduate of the University of Pennsylvania School of Medicine’s Masters of Bioethics program, has been awarded a Fulbright Grant for the 2009-2010 academic year. The Fulbright Program, established in 1946, is an international educational exchange program sp...

The nation’s home foreclosure epidemic may be taking its toll on Americans’ health as well as their wallets. Nearly half of people studied while undergoing foreclosure reported depressive symptoms, and 37 percent met screening criteria for major depression, according to new Univers...

Breast cancer survivors who lift weights are less likely than their non-weightlifting peers to experience worsening symptoms of lymphedema, the arm- and hand-swelling condition that plagues many women following surgery for their disease, according to new University of Pennsylva...

A new class of molecules capable of blocking the formation of specific protein clumps that are believed to contribute to the dementia of Alzheimer’s disease patients has been discovered by researchers at the University of Pennsylvania School of Medicine. By assaying close to 300,000 c...

A brain-preserving cooling treatment called therapeutic hypothermia is a cost-effective way to improve outcomes after out-of-hospital cardiac arrest, which claims the lives of more than 300,000 people each year in the United States and leaves thousands of others neurologically d...

Jill M. Baren, MD, MBE, an Associate Professor of Emergency Medicine and Pediatrics at the University of Pennsylvania School of Medicine, has been selected as a 2009-2010 fellow in the Hedwig van Ameringen Executive Leadership in Academic Medicine (ELAM) Program for Women at Drexel Un...

Jason Karlawish, MD, Associate Professor of Medicine and Medical Ethics at the University of Pennsylvania School of Medicine, and colleagues presented findings at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD 2009) from a survey of Ameri...

Thomas Cappola, MD, ScM, an assistant professor in the division of Cardiovascular Medicine at the University of Pennsylvania School of Medicine, has been honored with a Presidential Early Career Award for Scientists and Engineers. The award, the highest honor bestowed by the U.S. gover...

More pieces in the complex autism inheritance puzzle are emerging in the latest study from a research team including geneticists from the University of Pennsylvania School of Medicine, The Children’s Hospital of Philadelphia (CHOP), and several collaborating institutions. This st...

University of Pennsylvania School of Medicine scientists have been awarded $6.7 million from the National Institute of General Medical Sciences to investigate the role of molecular motors in cell biology. With this grant, the researchers will continue their studies of cytoskeletal m...

Jumping genes do most of their jumping, not during the development of sperm and egg cells, but during the development of the embryo itself. The research, published this month in Genes and Development, "challenges standard assumptions on the timing of when mobile DNA, so-called jumping...

Karen Glanz, a globally influential public-health scholar, has been named the ninth Penn Integrates Knowledge University Professor at the University of Pennsylvania. Glanz’s appointment will be shared between the School of Medicine and the School of Nursing, and she will lead a new c...

After a vaccination or an infection, the human immune system remembers to keep protecting against invaders it has already encountered, with the aid of specialized B-cells and T-cells. Immunological memory has long been the subject of intense study, but the underlying cellular mechan...

Researchers at the University of Pennsylvania School of Medicine have uncovered variation around two genes that are associated with an increased risk of testicular cancer. Testicular cancer is the most common cancer among young men, and its incidence among non-Hispanic Caucasian me...

In what researchers are calling a breakthrough, patients with thyroid cancer that is resistant to radioactive iodine therapy were found to respond well to sorafenib, a University of Pennsylvania School of Medicine researcher reported today at the annual meeting of the American Soci...

Related articles from Philadelphia Daily News, DG News and more.

Although the majority of patients with follicular lymphoma initially respond to chemotherapy, the disease frequently recurs, eventually becoming resistant to available therapies. Patients treated with traditional chemotherapy followed by a personalized vaccine were found to h...

Researchers at the University of Pennsylvania School of Medicine will receive $7.5 million over the next five years from the National Cancer Institute to find new ways to treat esophageal cancer, in addition to traditional chemoradiation. This research is a continuation of the group's...

Since 2000, nearly 1,000 "retail clinics" – offering routine care like sports physicals and immunizations and treatment for minor illnesses like strep throat – have opened their doors inside pharmacies and grocery stores across the United States. Retail chain operators proposed tha...

The University of Pennsylvania was honored by The American Society for Microbiology last Friday with a plaque dedication ceremony celebrating the designation of its third Milestones in Microbiology site. Formerly known as the Laboratory of Hygiene, the current Vagelos Laboratorie...

Women with ductal carcinoma in situ (DCIS) who exhibit an overexpression of the protein HER2/neu have a six-fold increase in risk of invasive breast cancer, according to a new study from the University of Pennsylvania School of Medicine. The results, published in the May issue of the jou...

Researchers at the University of Pennsylvania School of Medicine will receive $2 million over the next four years from the American Heart Association and the Jon Holden DeHaan Foundation to study how heart muscle cell regeneration can help improve outcomes for heart attack and heart f...

A University of Pennsylvania School of Medicine researcher has received a $100,000 Grand Challenges Explorations award from the Bill & Melinda Gates Foundation. The grant will support a global health research project conducted by Doron Greenbaum, PhD, Assistant Professor of Ph...

Women with chest pain are less likely than male patients to receive recommended, proven therapies while en route to the hospital, according to new research from the University of Pennsylvania School of Medicine. Despite evidence showing that the drugs aspirin and nitroglycerin are im...

The first long-term study following a large number of chest pain patients who are screened with coronary computerized tomographic angiography (CTA) confirms that the test is a safe, effective way to rule out serious cardiovascular disease in patients who come to hospital emergency r...

Jill M. Baren, MD, MBE, an Associate Professor of Emergency Medicine and Pediatrics at the University of Pennsylvania School of Medicine, will today become president of the Society for Academic Emergency Medicine, the nation’s largest organization devoted to research and education...

A research team led by Mitchell Lazar, MD, PhD, Director of the Institute for Diabetes, Obesity, and Metabolism at the University of Pennsylvania School of Medicine, has used state-of-the-art genetic technology to map thousands of positions where a molecular 'master regulator' of f...

Four School of Medicine professors, a School of Nursing professor, and the Chief Executive Officer of the University of Pennsylvania Health System, have been elected as members of the Institute of Medicine (IOM), one of the nation’s highest honors in biomedicine. The new members bring...

Women troubled by hot flashes and night sweats during the years around menopause want safe, effective treatment options. The University of Pennsylvania School of Medicine is part of a new National Institutes of Health (NIH) initiative to conduct clinical trials of promising treatmen...

Using the drug darapladib, researchers at the University of Pennsylvania School of Medicine and colleagues have inhibited a cholesterol-and immune system-associated protein, thereby reducing the development of heart-disease plaques that may cause death, heart attacks, and str...

Researchers at the University of Pennsylvania School of Medicine have discovered that a protein called FOXA2 controls genes that maintain the proper level of bile in the liver. FOXA2 may become the focus for new therapies to treat diseases that involve the regulation of bile salts. The st...

Researchers at the University of Pennsylvania School of Medicine have identified a potential new way to vaccinate against avian flu. By delivering vaccine via DNA constructed to build antigens against flu, along with a minute electric pulse, researchers have immunized experiment...

A $50 million gift from philanthropists Jerome and Anne Fisher will support a new eight-story biomedical-research center at the University of Pennsylvania dedicated to the growing field of translational medicine, which emphasizes an accelerated pace for converting laboratory di...

The US Senate Special Committee on Aging held a hearing in Washington, DC, this morning on older Americans and the significant barriers they face in exercising their right to vote. Jason Karlawish, MD, associate professor of Medicine and Medical Ethics at the University of Pennsylvani...

Marjorie Bowman, M.D., M.P.A., received the 2007 individual Association of American Medical Colleges Women in Medicine Leadership Development Award. Dr. Bowman is the Professor and Founding Chair of the Department of Family Medicine and Community Health and Director of the University’s C...

The Hospital of the University of Pennsylvania (HUP) has been selected for the "Honor Roll" of best hospitals in America by U.S.News and World Report, as featured in its July 25th issue. The publication's prestigious annual ranking of hospitals places HUP as one of only 18 hospitals chosen...